Drink wine handed out through a window as part of an age-old tradition.

A large grotto built in the 16th century amidst Florence's famous Boboli gardens.

The oldest operating pharmacy in the world features 800-year-old recipes.

The doodles of a genius line the walls of a secret room under the Medici Chapel, where they were hidden for nearly 500 years.

The middle finger of modernity.

Buried next to Pompeii, this lesser-known Roman villa was the opulent vacation home of Emperor Nero's wife.

This amazingly well-preserved villa just outside Pompeii boasts rare examples of ancient Roman paintings.

The walls and streets of the ancient city are peppered with penises.

An Italian crevasse filled with abandoned buildings gives visitors a look at the world without humans.

The only "Egyptian" pyramid in Europe and the legendary tomb of Remus.

A fairy tale castle in modern Rome.

2300-year-old Roman road connecting the empire.

The skull of the patron saint of lovers lies in the Basilica di Santa Maria in Cosmedin—maybe.

Museum dedicated to literary greats of the Romantic Period is also the home in which Keats met his untimely end.

Charles Dickens was not a fan of the ghastly wall dressings in this 6th century church.

This former Roman Catholic Church still contains the embalmed hearts and organs of 22 popes.

St. Francesca Romana, patron saint of drivers, resides in the church she founded.

One of several skulls claiming to belong to the beheaded St. John the Baptist is on display at this Roman church.

Installed in an act of one-upsmanship, the annual sundial in this church is also a symbolic victory for the Gregorian calendar.

More sculpture than building, this architecturally significant temple was built on the spot of Saint Peter's crucifixion.

An abandoned Roman salami factory has found new life as an art space home to 200 squatters.

The martyr's wax-enhanced skeletal remains lie preserved in a glass case in the Santa Maria della Vittoria in Rome.

The best preserved Paleochristian basilica in Rome hides a number of oddities and secrets.

This beautiful park on the outskirts of Rome protects the ruins of two colossal ancient aqueducts.